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Phosphoinositide Signaling Regulates the Exocyst Complex and Polarized Integrin Trafficking in Directionally Migrating Cells

Polarized delivery of signaling and adhesion molecules to the leading edge is required for directional migration of cells. Here, we describe a role for the PIP(2) synthesizing enzyme, PIPKIγi2, in regulation of exocyst complex control of cell polarity and polarized integrin trafficking during migrat...

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Detalhes bibliográficos
Main Authors: Thapa, Narendra, Sun, Yue, Schramp, Mark, Choi, Suyoung, Ling, Kun, Anderson, Richard A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266520/
https://ncbi.nlm.nih.gov/pubmed/22264730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.10.030
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