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Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy

Selective isotopic labeling provides an unparalleled window within which to study the structure and dynamics of RNAs by high resolution NMR spectroscopy. Unlike commonly used carbon sources, the asymmetry of (13)C-labeled pyruvate provides selective labeling in both the ribose and base moieties of n...

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Autors principals: Thakur, Chandar S., Dayie, T. Kwaku
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266500/
https://ncbi.nlm.nih.gov/pubmed/22089526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-011-9582-5
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