Glucose-Dependent Insulinotropic Polypeptide Reduces Fat-Specific Expression and Activity of 11β-Hydroxysteroid Dehydrogenase Type 1 and Inhibits Release of Free Fatty Acids

Glucose-dependent insulinotropic polypeptide (GIP) has been suggested to have direct effects on nonislet tissues. GIP also reportedly increased glucose uptake and inhibition of lipolysis in adipocytes after inhibition of the intracellular cortisone-cortisol shuttle 11β-hydroxysteroid dehydrogenase t...

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Bibliografiske detaljer
Main Authors: Gögebakan, Özlem, Andres, Janin, Biedasek, Katrin, Mai, Knut, Kühnen, Peter, Krude, Heiko, Isken, Frank, Rudovich, Natalia, Osterhoff, Martin A., Kintscher, Ulrich, Nauck, Michael, Pfeiffer, Andreas F.H., Spranger, Joachim
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2012
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266397/
https://ncbi.nlm.nih.gov/pubmed/22179810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0902
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