Free Fatty Acids Link Metabolism and Regulation of the Insulin-Sensitizing Fibroblast Growth Factor-21

OBJECTIVE: Fibroblast growth factor (FGF)-21 improves insulin sensitivity and lipid metabolism in obese or diabetic animal models, while human studies revealed increased FGF-21 levels in obesity and type 2 diabetes. Given that FGF-21 has been suggested to be a peroxisome proliferator–activator recep...

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Bibliografiska uppgifter
Huvudupphovsmän: Mai, Knut, Andres, Janin, Biedasek, Katrin, Weicht, Jessica, Bobbert, Thomas, Sabath, Markus, Meinus, Sabine, Reinecke, Franziska, Möhlig, Matthias, Weickert, Martin O., Clemenz, Markus, Pfeiffer, Andreas F.H., Kintscher, Ulrich, Spuler, Simone, Spranger, Joachim
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2009
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Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699854/
https://ncbi.nlm.nih.gov/pubmed/19401423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1775
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