Glucose-Dependent Insulinotropic Polypeptide Reduces Fat-Specific Expression and Activity of 11β-Hydroxysteroid Dehydrogenase Type 1 and Inhibits Release of Free Fatty Acids

Glucose-dependent insulinotropic polypeptide (GIP) has been suggested to have direct effects on nonislet tissues. GIP also reportedly increased glucose uptake and inhibition of lipolysis in adipocytes after inhibition of the intracellular cortisone-cortisol shuttle 11β-hydroxysteroid dehydrogenase t...

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Main Authors: Gögebakan, Özlem, Andres, Janin, Biedasek, Katrin, Mai, Knut, Kühnen, Peter, Krude, Heiko, Isken, Frank, Rudovich, Natalia, Osterhoff, Martin A., Kintscher, Ulrich, Nauck, Michael, Pfeiffer, Andreas F.H., Spranger, Joachim
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2012
主題:
Metabolism
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266397/
https://ncbi.nlm.nih.gov/pubmed/22179810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0902
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