LDL Receptor Knock-Out Mice Are a Physiological Model Particularly Vulnerable to Study the Onset of Inflammation in Non-Alcoholic Fatty Liver Disease

BACKGROUND & AIMS: Non-alcoholic steatohepatitis (NASH) involves steatosis combined with inflammation, which can progress into fibrosis and cirrhosis. Exploring the molecular mechanisms of NASH is highly dependent on the availability of animal models. Currently, the most commonly used animal mod...

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Detalhes bibliográficos
Main Authors: Bieghs, Veerle, Van Gorp, Patrick J., Wouters, Kristiaan, Hendrikx, Tim, Gijbels, Marion J., van Bilsen, Marc, Bakker, Jaap, Binder, Christoph J., Lütjohann, Dieter, Staels, Bart, Hofker, Marten H., Shiri-Sverdlov, Ronit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266276/
https://ncbi.nlm.nih.gov/pubmed/22295101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030668
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