LDL Receptor Knock-Out Mice Are a Physiological Model Particularly Vulnerable to Study the Onset of Inflammation in Non-Alcoholic Fatty Liver Disease

BACKGROUND & AIMS: Non-alcoholic steatohepatitis (NASH) involves steatosis combined with inflammation, which can progress into fibrosis and cirrhosis. Exploring the molecular mechanisms of NASH is highly dependent on the availability of animal models. Currently, the most commonly used animal mod...

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Main Authors: Bieghs, Veerle, Van Gorp, Patrick J., Wouters, Kristiaan, Hendrikx, Tim, Gijbels, Marion J., van Bilsen, Marc, Bakker, Jaap, Binder, Christoph J., Lütjohann, Dieter, Staels, Bart, Hofker, Marten H., Shiri-Sverdlov, Ronit
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266276/
https://ncbi.nlm.nih.gov/pubmed/22295101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030668
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