LDL Receptor Knock-Out Mice Are a Physiological Model Particularly Vulnerable to Study the Onset of Inflammation in Non-Alcoholic Fatty Liver Disease

BACKGROUND & AIMS: Non-alcoholic steatohepatitis (NASH) involves steatosis combined with inflammation, which can progress into fibrosis and cirrhosis. Exploring the molecular mechanisms of NASH is highly dependent on the availability of animal models. Currently, the most commonly used animal mod...

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Bibliografiska uppgifter
Huvudupphovsmän: Bieghs, Veerle, Van Gorp, Patrick J., Wouters, Kristiaan, Hendrikx, Tim, Gijbels, Marion J., van Bilsen, Marc, Bakker, Jaap, Binder, Christoph J., Lütjohann, Dieter, Staels, Bart, Hofker, Marten H., Shiri-Sverdlov, Ronit
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266276/
https://ncbi.nlm.nih.gov/pubmed/22295101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030668
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