A carregar...
Discovery of a novel and potent class of F. tularensis enoyl-reductase (FabI) inhibitors by molecular shape and electrostatic matching
Enoyl-acyl carrier protein (ACP) reductase, FabI, is a key enzyme in the bacterial fatty acid biosynthesis pathway (FAS II). FabI is an NADH-dependent oxidoreductase that acts to reduce enoyl-ACP substrates in a final step of the pathway. The absence of this enzyme in humans makes it an attractive t...
Na minha lista:
Main Authors: | , , , , , , , , |
---|---|
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
|
Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266168/ https://ncbi.nlm.nih.gov/pubmed/22098466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201168g |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|