Study of Genotypic and Phenotypic HIV-1 Dynamics of Integrase Mutations During Raltegravir Treatment: A Refined Analysis by Ultra-Deep 454 Pyrosequencing

Background. The dynamics of raltegravir-resistant variants and their impact on virologic response in 23 HIV-1–infected patients, who started a salvage raltegravir-containing regimen, were investigated. Methods. Integrase population sequencing and Ultra-Deep-454 Pyrosequencing (UDPS) were performed o...

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Hauptverfasser: Armenia, Daniele, Vandenbroucke, Ina, Fabeni, Lavinia, Van Marck, Herwig, Cento, Valeria, D’Arrigo, Roberta, Van Wesenbeeck, Liesbeth, Scopelliti, Fernanda, Micheli, Valeria, Bruzzone, Bianca, Lo Caputo, Sergio, Aerssens, Jeroen, Rizzardini, Giuliano, Tozzi, Valerio, Narciso, Pasquale, Antinori, Andrea, Stuyver, Lieven, Perno, Carlo Federico, Ceccherini-Silberstein, Francesca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
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Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266134/
https://ncbi.nlm.nih.gov/pubmed/22238474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir821
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