Study of Genotypic and Phenotypic HIV-1 Dynamics of Integrase Mutations During Raltegravir Treatment: A Refined Analysis by Ultra-Deep 454 Pyrosequencing

Background. The dynamics of raltegravir-resistant variants and their impact on virologic response in 23 HIV-1–infected patients, who started a salvage raltegravir-containing regimen, were investigated. Methods. Integrase population sequencing and Ultra-Deep-454 Pyrosequencing (UDPS) were performed o...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Armenia, Daniele, Vandenbroucke, Ina, Fabeni, Lavinia, Van Marck, Herwig, Cento, Valeria, D’Arrigo, Roberta, Van Wesenbeeck, Liesbeth, Scopelliti, Fernanda, Micheli, Valeria, Bruzzone, Bianca, Lo Caputo, Sergio, Aerssens, Jeroen, Rizzardini, Giuliano, Tozzi, Valerio, Narciso, Pasquale, Antinori, Andrea, Stuyver, Lieven, Perno, Carlo Federico, Ceccherini-Silberstein, Francesca
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2012
Θέματα:
Major Articles and Brief Reports
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266134/
https://ncbi.nlm.nih.gov/pubmed/22238474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir821
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