Successful Microbubble Sonothrombolysis without Tissue Plasminogen Activator in a Rabbit Model of Acute Ischemic Stroke

BACKGROUND: Microbubbles (MB) combined with ultrasound (US) have been shown to lyse clots without tissue plasminogen activator (tPA) both in vitro and in vivo. We evaluated sonothrombolysis with three types of MB using a rabbit embolic stroke model. METHODS: New Zealand White rabbits (n=74) received...

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Hlavní autoři: Culp, William C., Flores, Rene, Brown, Aliza T., Lowery, John D., Roberson, Paula K., Hennings, Leah J., Woods, Sean D., Hatton, Jeff H., Culp, Benjamin C., Skinner, Robert D., Borrelli, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266124/
https://ncbi.nlm.nih.gov/pubmed/21700942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.607150
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