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Microbubbles Improve Sonothrombolysis In Vitro and Decrease Hemorrhage In Vivo in a Rabbit Stroke Model

INTRODUCTION: Tissue plasminogen activator (tPA) is the thrombolytic standard of care for acute ischemic stroke, but intracerebral hemorrhage (ICH) remains a common and devastating complication. We investigated using ultrasound (US) and microbubble (MB) techniques to reduce required tPA doses and to...

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Detalhes bibliográficos
Main Authors: Brown, Aliza T., Flores, Rene, Hamilton, Eric, Roberson, Paula K., Borrelli, Michael J., Culp, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845811/
https://ncbi.nlm.nih.gov/pubmed/21150788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/RLI.0b013e318200757a
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