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De novo discovery of mutated driver pathways in cancer

Next-generation DNA sequencing technologies are enabling genome-wide measurements of somatic mutations in large numbers of cancer patients. A major challenge in the interpretation of these data is to distinguish functional “driver mutations” important for cancer development from random “passenger mu...

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Bibliografski detalji
Glavni autori: Vandin, Fabio, Upfal, Eli, Raphael, Benjamin J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266044/
https://ncbi.nlm.nih.gov/pubmed/21653252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.120477.111
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