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De novo discovery of mutated driver pathways in cancer
Next-generation DNA sequencing technologies are enabling genome-wide measurements of somatic mutations in large numbers of cancer patients. A major challenge in the interpretation of these data is to distinguish functional “driver mutations” important for cancer development from random “passenger mu...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266044/ https://ncbi.nlm.nih.gov/pubmed/21653252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.120477.111 |
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