Amyloid Deposition Begins in the Striatum of Presenilin-1 Mutation Carriers from Two Unrelated Pedigrees

The amyloid cascade hypothesis suggests that the aggregation and deposition of amyloid-β protein is an initiating event in Alzheimer's disease (AD). Using amyloid imaging technology, such as the positron emission tomography (PET) agent Pittsburgh compound-B (PiB), it is possible to explore the...

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Main Authors: Klunk, William E., Price, Julie C., Mathis, Chester A., Tsopelas, Nicholas D., Lopresti, Brian J., Ziolko, Scott K., Bi, Wenzhu, Hoge, Jessica A., Cohen, Ann D., Ikonomovic, Milos D., Saxton, Judith A., Snitz, Beth E., Pollen, Daniel A., Moonis, Majaz, Lippa, Carol F., Swearer, Joan M., Johnson, Keith A., Rentz, Dorene M., Fischman, Alan J., Aizenstein, Howard J., DeKosky, Steven T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265970/
https://ncbi.nlm.nih.gov/pubmed/17553989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0730-07.2007
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