Basal Cerebral Metabolism May Modulate the Cognitive Effects of Aβ in Mild Cognitive Impairment: An Example of Brain Reserve

Inverse correlations between amyloid-β (Aβ) load measured by Pittsburgh Compound-B (PiB) positron emission tomography (PET) and cerebral metabolism using [(18)F]fluoro-2-deoxy-d-glucose (FDG) in Alzheimer's disease (AD) patients, suggest local Aβ-induced metabolic insults. However, this relatio...

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Detalhes bibliográficos
Main Authors: Cohen, Ann D., Price, Julie C., Weissfeld, Lisa A., James, Jeffrey, Rosario, Bedda L., Bi, Wenzhu, Nebes, Robert D., Saxton, Judith A., Snitz, Beth E., Aizenstein, Howard A., Wolk, David A., DeKosky, Steven T., Mathis, Chester A., Klunk, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810461/
https://ncbi.nlm.nih.gov/pubmed/19940172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3669-09.2009
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