Basal Cerebral Metabolism May Modulate the Cognitive Effects of Aβ in Mild Cognitive Impairment: An Example of Brain Reserve

Inverse correlations between amyloid-β (Aβ) load measured by Pittsburgh Compound-B (PiB) positron emission tomography (PET) and cerebral metabolism using [(18)F]fluoro-2-deoxy-d-glucose (FDG) in Alzheimer's disease (AD) patients, suggest local Aβ-induced metabolic insults. However, this relatio...

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Main Authors: Cohen, Ann D., Price, Julie C., Weissfeld, Lisa A., James, Jeffrey, Rosario, Bedda L., Bi, Wenzhu, Nebes, Robert D., Saxton, Judith A., Snitz, Beth E., Aizenstein, Howard A., Wolk, David A., DeKosky, Steven T., Mathis, Chester A., Klunk, William E.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2009
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810461/
https://ncbi.nlm.nih.gov/pubmed/19940172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3669-09.2009
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