Basal Cerebral Metabolism May Modulate the Cognitive Effects of Aβ in Mild Cognitive Impairment: An Example of Brain Reserve

Inverse correlations between amyloid-β (Aβ) load measured by Pittsburgh Compound-B (PiB) positron emission tomography (PET) and cerebral metabolism using [(18)F]fluoro-2-deoxy-d-glucose (FDG) in Alzheimer's disease (AD) patients, suggest local Aβ-induced metabolic insults. However, this relatio...

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Main Authors: Cohen, Ann D., Price, Julie C., Weissfeld, Lisa A., James, Jeffrey, Rosario, Bedda L., Bi, Wenzhu, Nebes, Robert D., Saxton, Judith A., Snitz, Beth E., Aizenstein, Howard A., Wolk, David A., DeKosky, Steven T., Mathis, Chester A., Klunk, William E.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810461/
https://ncbi.nlm.nih.gov/pubmed/19940172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3669-09.2009
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