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Loss of Daylight Vision in Retinal Degeneration: Are Oxidative Stress and Metabolic Dysregulation to Blame?

Retinitis pigmentosa is characterized by loss of night vision, followed by complete blindness. Over 40 genetic loci for retinitis pigmentosa have been identified in humans, primarily affecting photoreceptor structure and function. The availability of excellent animal models allows for a mechanistic...

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Autors principals: Punzo, Claudio, Xiong, Wenjun, Cepko, Constance L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265845/
https://ncbi.nlm.nih.gov/pubmed/22074929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R111.304428
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