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Molecular regulations governing TREK and TRAAK channel functions

K(+) channels with two-pore domain (K(2p)) form a large family of hyperpolarizing channels. They produce background currents that oppose membrane depolarization and cell excitability. They are involved in cellular mechanisms of apoptosis, vasodilatation, anesthesia, pain, neuroprotection and depress...

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Autors principals: Noël, Jacques, Sandoz, Guillaume, Lesage, Florian
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265763/
https://ncbi.nlm.nih.gov/pubmed/21829087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.5.16469
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