Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death

Functional telomeres are protected from non-homologous end-joining (NHEJ) and homologous recombination (HR) DNA repair pathways. Replication is a critical period for telomeres because of the requirement for reconstitution of functional protected telomere conformations, a process that involves DNA re...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gauthier, Laurent R., Granotier, Christine, Hoffschir, Françoise, Etienne, Olivier, Ayouaz, Ali, Desmaze, Chantal, Mailliet, Patrick, Biard, Denis S., Boussin, François D.
Formato: Artigo
Idioma:Inglês
Publicado em: SP Birkhäuser Verlag Basel 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265728/
https://ncbi.nlm.nih.gov/pubmed/21773671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0767-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados