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Methylation-dependent DNA Restriction in Bacillus anthracis

Bacillus anthracis, the causative agent of anthrax, is poorly transformed with DNA that is methylated on adenine or cytosine. Here we characterize three genetic loci encoding type IV methylation-dependent restriction enzymes that target DNA containing C5-methylcytosine (m5C). Strains in which these...

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Bibliografiske detaljer
Main Authors: Sitaraman, Ramakrishnan, Leppla, Stephen H.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265652/
https://ncbi.nlm.nih.gov/pubmed/22178763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2011.11.061
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