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Methylation-dependent DNA Restriction in Bacillus anthracis

Bacillus anthracis, the causative agent of anthrax, is poorly transformed with DNA that is methylated on adenine or cytosine. Here we characterize three genetic loci encoding type IV methylation-dependent restriction enzymes that target DNA containing C5-methylcytosine (m5C). Strains in which these...

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Autors principals: Sitaraman, Ramakrishnan, Leppla, Stephen H.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265652/
https://ncbi.nlm.nih.gov/pubmed/22178763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2011.11.061
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