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Fasudil Decreases Lesion Burden in a Murine Model of Cerebral Cavernous Malformation Disease
BACKGROUND AND PURPOSE: Cerebral cavernous malformations (CCMs) are characterized by grossly dilated capillaries, associated with vascular leak and hemorrhage, and occur in sporadic or inherited (autosomal dominant) forms with mutations in one of three gene loci (CCM 1, 2 or 3). We previously report...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265629/ https://ncbi.nlm.nih.gov/pubmed/22034008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.625467 |
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