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Construction of Cyclopentanol Derivatives via Three-Component Coupling of Silyl Glyoxylates, Acetylides, and Nitroalkenes

[Image: see text] The three-component coupling of Mg-acetylides, silyl glyoxylates, and nitroalkenes results in a highly diastereoselective Kuwajima-Reich/vinylogous Michael cascade that provides tetrasubstituted silyloxyallene products. The regio- and diastereoselectivity were studied using DFT cal...

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Bibliografiske detaljer
Main Authors: Boyce, Gregory R., Liu, Shubin, Johnson, Jeffrey S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265386/
https://ncbi.nlm.nih.gov/pubmed/22235777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2033527
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