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Editing of human K(V)1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity

In the nervous system, A→I RNA editing has an important role in regulating neuronal excitability. Ligand-gated membrane receptors, synaptic proteins, as well as ion channels, are targets for recoding by RNA editing. Although scores of editing sites have been identified in the mammalian brain, little...

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Detalhes bibliográficos
Main Authors: Gonzalez, Carlos, Lopez-Rodriguez, Angelica, Srikumar, Deepa, Rosenthal, Joshua J.C., Holmgren, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265383/
https://ncbi.nlm.nih.gov/pubmed/21847110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1446
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