Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

A major barrier to research on Parkinson's disease is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells from patients and differentiate them into neurons affected by disease. Triplication of SNCA, encoding α-synuclein, causes a fully penetran...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Devine, Michael J., Ryten, Mina, Vodicka, Petr, Thomson, Alison J., Burdon, Tom, Houlden, Henry, Cavaleri, Fatima, Nagano, Masumi, Drummond, Nicola J., Taanman, Jan-Willem, Schapira, Anthony H., Gwinn, Katrina, Hardy, John, Lewis, Patrick A., Kunath, Tilo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265381/
https://ncbi.nlm.nih.gov/pubmed/21863007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1453
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi