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Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
A major barrier to research on Parkinson's disease is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells from patients and differentiate them into neurons affected by disease. Triplication of SNCA, encoding α-synuclein, causes a fully penetran...
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| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Pub. Group
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265381/ https://ncbi.nlm.nih.gov/pubmed/21863007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1453 |
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