Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

A major barrier to research on Parkinson's disease is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells from patients and differentiate them into neurons affected by disease. Triplication of SNCA, encoding α-synuclein, causes a fully penetran...

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Detaylı Bibliyografya
Asıl Yazarlar: Devine, Michael J., Ryten, Mina, Vodicka, Petr, Thomson, Alison J., Burdon, Tom, Houlden, Henry, Cavaleri, Fatima, Nagano, Masumi, Drummond, Nicola J., Taanman, Jan-Willem, Schapira, Anthony H., Gwinn, Katrina, Hardy, John, Lewis, Patrick A., Kunath, Tilo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265381/
https://ncbi.nlm.nih.gov/pubmed/21863007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1453
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