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Somatic Alpha-Synuclein Mutations in Parkinson's Disease: Hypothesis and Preliminary Data
Alpha-synuclein (SNCA) is crucial in the pathogenesis of Parkinson's disease (PD), yet mutations in the SNCA gene are rare. Evidence for somatic genetic variation in normal humans, also involving the brain, is increasing, but its role in disease is unknown. Somatic SNCA mutations, arising in ea...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3739940/ https://ncbi.nlm.nih.gov/pubmed/23674490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25502 |
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