TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a

There is increasing evidence that miRNA and transcription factors interact in an instructive fashion in normal and malignant hematopoiesis. We explored the impact of TEL-AML1 (ETV6-RUNX1), the most common fusion protein in childhood leukemia, on miRNA expression and the leukemic phenotype. Using RNA...

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Bibliographic Details
Main Authors: Diakos, Christofer, Zhong, Sheng, Xiao, Yuanyuan, Zhou, Mi, Vasconcelos, Gisele M., Krapf, Gerd, Yeh, Ru-Fang, Zheng, Shichun, Kang, Michelle, Wiencke, John K., Pombo-de-Oliveira, Maria S., Panzer-Grümayer, Renate, Wiemels, Joseph L.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Lymphoid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265147/
https://ncbi.nlm.nih.gov/pubmed/20807887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-206706
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