Reciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice

Heme oxygenase (HO) system is one of the key regulators of cellular redox homeostasis which responds to oxidative stress (ROS) via HO-1 induction. However, recent reports have suggested an inhibitory effect of ROS on HO activity. In light of these conflicting reports, this study was designed to eval...

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Hlavní autoři: Kawakami, Tomoko, Puri, Nitin, Sodhi, Komal, Bellner, Lars, Takahashi, Toru, Morita, Kiyoshi, Rezzani, Rita, Oury, Tim D., Abraham, Nader G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265091/
https://ncbi.nlm.nih.gov/pubmed/22292113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/740203
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