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Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development
We performed an in depth analysis of Bmp4, a critical regulator of development, disease, and evolution, in cranial neural crest (CNC). Conditional Bmp4 overexpression, using a tetracycline-regulated Bmp4 gain-of-function allele, resulted in facial skeletal changes that were most dramatic after an E1...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265059/ https://ncbi.nlm.nih.gov/pubmed/22219353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.073197 |
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