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Bmp signaling represses Vegfa to promote outflow tract cushion development
Congenital heart disease (CHD) is a devastating anomaly that affects ∼1% of live births. Defects of the outflow tract (OFT) make up a large percentage of human CHD. We investigated Bmp signaling in mouse OFT development by conditionally deleting both Bmp4 and Bmp7 in the second heart field (SHF). SH...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3737720/ https://ncbi.nlm.nih.gov/pubmed/23863481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.097360 |
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