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Probing the substrate specificity of the bacterial Pnkp/Hen1 RNA repair system using synthetic RNAs

Ribotoxins cleave essential RNAs involved in protein synthesis as a strategy for cell killing. RNA repair systems exist in nature to counteract the lethal actions of ribotoxins, as first demonstrated by the RNA repair system from bacteriophage T4 25 yr ago. Recently, we found that two bacterial prot...

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Detalhes bibliográficos
Main Authors: Zhang, Can, Chan, Chio Mui, Wang, Pei, Huang, Raven H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264919/
https://ncbi.nlm.nih.gov/pubmed/22190744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.030502.111
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