DUX4 activates germline genes, retroelements and immune-mediators: Implications for facioscapulohumeral dystrophy

Facioscapulohumeral dystrophy (FSHD) is one of the most common inherited muscular dystrophies. The causative gene remains controversial and the mechanism of pathophysiology unknown. Here we identify genes associated with germline and early stem cell development as targets of the DUX4 transcription f...

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Auteurs principaux: Geng, Linda N., Yao, Zizhen, Snider, Lauren, Fong, Abraham P., Cech, Jennifer N., Young, Janet M, van der Maarel, Silvere M., Ruzzo, Walter L., Gentleman, Robert C., Tawil, Rabi, Tapscott, Stephen J.
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264808/
https://ncbi.nlm.nih.gov/pubmed/22209328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.11.013
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