Paraquat, but Not Maneb, Induces Synucleinopathy and Tauopathy in Striata of Mice through Inhibition of Proteasomal and Autophagic Pathways

SNCA and MAPT genes and environmental factors are important risk factors of Parkinson's disease [PD], the second-most common neurodegenerative disease. The agrichemicals maneb and paraquat selectively target dopaminergic neurons, leading to parkinsonism, through ill-defined mechanisms. In the c...

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Detaylı Bibliyografya
Asıl Yazarlar: Wills, Jonathan, Credle, Joel, Oaks, Adam W., Duka, Valeriy, Lee, Jae-Hoon, Jones, Jessica, Sidhu, Anita
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264632/
https://ncbi.nlm.nih.gov/pubmed/22292029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030745
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