ELEVATED TAUOPATHY AND ALPHA SYNUCLEIN PATHOLOGY IN POSTMORTEM PARKINSON’S DISEASE BRAINS WITH AND WITHOUT DEMENTIA

Parkinson’s disease [PD], a progressive neurodegenerative disease, results in abnormal accumulation of insoluble alpha-synuclein [α-Syn] in dopaminergic neurons. Here we examined tauopathic changes and the α-Syn/p-GSK-3β/proteasome pathway in postmortem striata and inferior frontal gyri [IFG] from p...

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Bibliografiska uppgifter
Huvudupphovsmän: Wills, Jonathan, Jones, Jessica, Haggerty, Thomas, Duka, Valeriy, Joyce, Jeffrey N., Sidhu, Anita
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922478/
https://ncbi.nlm.nih.gov/pubmed/20599975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.06.017
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