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Forebrain Deletion of αGDI in Adult Mice Worsens the Pre-Synaptic Deficit at Cortico-Lateral Amygdala Synaptic Connections

The GDI1 gene encodes αGDI, which retrieves inactive GDP-bound RAB from membranes to form a cytosolic pool awaiting vesicular release. Mutations in GDI1 are responsible for X-linked Intellectual Disability. Characterization of the Gdi1-null mice has revealed alterations in the total number and distr...

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Main Authors: Bianchi, Veronica, Gambino, Frédéric, Muzio, Luca, Toniolo, Daniela, Humeau, Yann, D'Adamo, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264564/
https://ncbi.nlm.nih.gov/pubmed/22291894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029763
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