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Inoculation of Swine with Foot-and-Mouth Disease SAP-Mutant Virus Induces Early Protection against Disease

Foot-and-mouth disease virus (FMDV) leader proteinase (L(pro)) cleaves itself from the viral polyprotein and cleaves the translation initiation factor eIF4G. As a result, host cell translation is inhibited, affecting the host innate immune response. We have demonstrated that L(pro) is also associate...

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Detalhes bibliográficos
Main Authors: Díaz-San Segundo, Fayna, Weiss, Marcelo, Pérez-Martín, Eva, Dias, Camila C., Grubman, Marvin J., de los Santos, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264347/
https://ncbi.nlm.nih.gov/pubmed/22114339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05941-11
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