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Interferon-Induced Protection against Foot-and-Mouth Disease Virus Infection Correlates with Enhanced Tissue-Specific Innate Immune Cell Infiltration and Interferon-Stimulated Gene Expression

Previously, we demonstrated that type I interferon (IFN-α/β) or a combination of IFN-α/β and type II IFN (IFN-γ) delivered by a replication-defective human adenovirus 5 (Ad5) vector protected swine when challenged 1 day later with foot-and-mouth disease virus (FMDV). To gain a more comprehensive und...

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Main Authors: Diaz-San Segundo, Fayna, Moraes, Mauro P., de los Santos, Teresa, Dias, Camila C. A., Grubman, Marvin J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology (ASM) 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812365/
https://ncbi.nlm.nih.gov/pubmed/19955313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01874-09
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