A Conserved Domain in the Leader Proteinase of Foot-and-Mouth Disease Virus Is Required for Proper Subcellular Localization and Function

The leader proteinase (L(pro)) of foot-and-mouth disease virus (FMDV) is involved in antagonizing the innate immune response by blocking the expression of interferon (IFN) and by reducing the immediate-early induction of IFN-β mRNA and IFN-stimulated genes. In addition to its role in shutting off ca...

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Detalhes bibliográficos
Main Authors: de los Santos, Teresa, Diaz-San Segundo, Fayna, Zhu, James, Koster, Marla, Dias, Camila C. A., Grubman, Marvin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643771/
https://ncbi.nlm.nih.gov/pubmed/19052079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02112-08
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