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Monoclonal Antibodies Neutralize Bacillus cereus Nhe Enterotoxin by Inhibiting Ordered Binding of Its Three Exoprotein Components

The Nhe enterotoxin from Bacillus cereus is known to induce cytotoxicity on Vero and CaCo-2 cells by ordered binding of its single components NheA, NheB, and NheC. This study aimed to elucidate functional sites on NheB by identifying the epitopes of the neutralizing monoclonal antibodies 1E11 and 2B...

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Autors principals: Didier, Andrea, Dietrich, Richard, Gruber, Stephanie, Bock, Stefanie, Moravek, Maximilian, Nakamura, Tadashi, Lindbäck, Toril, Granum, Per Einar, Märtlbauer, Erwin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264321/
https://ncbi.nlm.nih.gov/pubmed/22104106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05681-11
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