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Complex Formation between NheB and NheC Is Necessary to Induce Cytotoxic Activity by the Three-Component Bacillus cereus Nhe Enterotoxin

The nonhemolytic enterotoxin (Nhe) is known as a major pathogenicity factor for the diarrheal type of food poisoning caused by Bacillus cereus. The Nhe complex consists of NheA, NheB and NheC, all of them required to reach maximum cytotoxicity following a specific binding order on cell membranes. He...

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Bibliographic Details
Main Authors: Heilkenbrinker, Uta, Dietrich, Richard, Didier, Andrea, Zhu, Kui, Lindbäck, Toril, Granum, Per Einar, Märtlbauer, Erwin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639968/
https://ncbi.nlm.nih.gov/pubmed/23646182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063104
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