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Monoclonal Antibodies Neutralize Bacillus cereus Nhe Enterotoxin by Inhibiting Ordered Binding of Its Three Exoprotein Components

The Nhe enterotoxin from Bacillus cereus is known to induce cytotoxicity on Vero and CaCo-2 cells by ordered binding of its single components NheA, NheB, and NheC. This study aimed to elucidate functional sites on NheB by identifying the epitopes of the neutralizing monoclonal antibodies 1E11 and 2B...

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Detalhes bibliográficos
Main Authors: Didier, Andrea, Dietrich, Richard, Gruber, Stephanie, Bock, Stefanie, Moravek, Maximilian, Nakamura, Tadashi, Lindbäck, Toril, Granum, Per Einar, Märtlbauer, Erwin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264321/
https://ncbi.nlm.nih.gov/pubmed/22104106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05681-11
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