PD 404,182 Is a Virocidal Small Molecule That Disrupts Hepatitis C Virus and Human Immunodeficiency Virus

We describe a virucidal small molecule, PD 404,182, that is effective against hepatitis C virus (HCV) and human immunodeficiency virus (HIV). The median 50% inhibitory concentrations (IC(50)s) for the antiviral effect of PD 404,182 against HCV and HIV in cell culture are 11 and 1 μM, respectively. T...

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Bibliografiske detaljer
Main Authors: Chamoun, Ana Maria, Chockalingam, Karuppiah, Bobardt, Michael, Simeon, Rudo, Chang, Jinhong, Gallay, Philippe, Chen, Zhilei
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264232/
https://ncbi.nlm.nih.gov/pubmed/22083468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05722-11
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