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Phenothiazines Inhibit Hepatitis C Virus Entry, Likely by Increasing the Fluidity of Cholesterol-Rich Membranes

Despite recent progress in the development of direct-acting antiviral agents against hepatitis C virus (HCV), more effective therapies are still urgently needed. We and others previously identified three phenothiazine compounds as potent HCV entry inhibitors. In this study, we show that phenothiazin...

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Detalhes bibliográficos
Main Authors: Chamoun-Emanuelli, Ana M., Pecheur, Eve-Isabelle, Simeon, Rudo L., Huang, Da, Cremer, Paul S., Chen, Zhilei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716126/
https://ncbi.nlm.nih.gov/pubmed/23529728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02593-12
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