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Chronic Methadone Treatment Shows a Better Cost/Benefit Ratio than Chronic Morphine in Mice

Chronic treatment of pain with opiate drugs can lead to analgesic tolerance and drug dependence. Although all opiate drugs can promote tolerance and dependence in practice, the severity of those unwanted side effects differs depending on the drug used. Although each opiate drug has its own unique se...

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Detalles Bibliográficos
Main Authors: Enquist, Johan, Ferwerda, Madeline, Milan-Lobo, Laura, Whistler, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263965/
https://ncbi.nlm.nih.gov/pubmed/22062352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.187583
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