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Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells

ATP-binding cassette (ABC) drug transporters ABCB1 [P-glycoprotein (Pgp)] and ABCG2 are expressed in many tissues including those of the intestines, the liver, the kidney and the brain and are known to influence the pharmacokinetics and toxicity of therapeutic drugs. In vitro studies involving their...

詳細記述

保存先:
書誌詳細
主要な著者: Shukla, Suneet, Schwartz, Candice, Kapoor, Khyati, Kouanda, Abdul, Ambudkar, Suresh V.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263938/
https://ncbi.nlm.nih.gov/pubmed/22041108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.042721
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