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Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells

ATP-binding cassette (ABC) drug transporters ABCB1 [P-glycoprotein (Pgp)] and ABCG2 are expressed in many tissues including those of the intestines, the liver, the kidney and the brain and are known to influence the pharmacokinetics and toxicity of therapeutic drugs. In vitro studies involving their...

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מידע ביבליוגרפי
Main Authors: Shukla, Suneet, Schwartz, Candice, Kapoor, Khyati, Kouanda, Abdul, Ambudkar, Suresh V.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Pharmacology and Experimental Therapeutics 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263938/
https://ncbi.nlm.nih.gov/pubmed/22041108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.042721
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