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Use of Baculovirus BacMam Vectors for Expression of ABC Drug Transporters in Mammalian Cells
ATP-binding cassette (ABC) drug transporters ABCB1 [P-glycoprotein (Pgp)] and ABCG2 are expressed in many tissues including those of the intestines, the liver, the kidney and the brain and are known to influence the pharmacokinetics and toxicity of therapeutic drugs. In vitro studies involving their...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263938/ https://ncbi.nlm.nih.gov/pubmed/22041108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.042721 |
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