Preparation of oligodeoxyribonucleoside methylphosphonates on a polystyrene support.

An efficient procedure is described for synthesizing deoxyribonucleoside methylphosphonates on polystyrene polymer supports which involves condensing 5'-dimethoxytrityldeoxynucleoside 3'-methylphosphonates. The oligomers are removed from the support and the base protecting groups hydrolyze...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Miller, P S, Agris, C H, Murakami, A, Reddy, P M, Spitz, S A, Ts'o, P O
Format: Artigo
Language:Inglês
Published: Oxford University Press 1983
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6622255/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.18.6225
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