Preparation of oligodeoxyribonucleoside methylphosphonates on a polystyrene support.

An efficient procedure is described for synthesizing deoxyribonucleoside methylphosphonates on polystyrene polymer supports which involves condensing 5'-dimethoxytrityldeoxynucleoside 3'-methylphosphonates. The oligomers are removed from the support and the base protecting groups hydrolyze...

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Main Authors: Miller, P S, Agris, C H, Murakami, A, Reddy, P M, Spitz, S A, Ts'o, P O
Formato: Artigo
Idioma:Inglês
Publicado: 1983
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC326369/
https://ncbi.nlm.nih.gov/pubmed/6622255
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