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A New Aryl Hydrocarbon Receptor Homology Model Targeted to Improve Docking Reliability

The aryl hydrocarbon receptor (AhR) is a ligand-dependent, basic helix-loop-helix Per-ARNT-Sim (PAS) containing transcription factor that can bind and be activated by structurally diverse chemicals, including the toxic environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). As no exper...

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Bibliographic Details
Main Authors: Motto, Ilaria, Bordogna, Annalisa, Soshilov, Anatoly A., Denison, Michael S., Bonati, Laura
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263330/
https://ncbi.nlm.nih.gov/pubmed/21981577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci2001617
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