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A New Aryl Hydrocarbon Receptor Homology Model Targeted to Improve Docking Reliability
The aryl hydrocarbon receptor (AhR) is a ligand-dependent, basic helix-loop-helix Per-ARNT-Sim (PAS) containing transcription factor that can bind and be activated by structurally diverse chemicals, including the toxic environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). As no exper...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263330/ https://ncbi.nlm.nih.gov/pubmed/21981577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci2001617 |
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